Coagulation Topic Center

Below are the College of American Pathologist's (CAP) Coagulation Committee's primary resources on coagulation and related topics.

Coagulation Surveys – Discussions of Interest

• INR Discussion (PDF, 41 K)
• Special INR Discussion (PDF, 63 K)
• Heparin Calibration Curve (PDF, 45 K)
• D-Dimer Discussion (PDF, 37 K)
• ADAMTS13 Discussion (PDF, 122 K)

CAP Press Publications

The following publication is available through the CAP Press Publications.

• An Algorithmic Approach to Hemostasis Testing

CAP Conference XXXVI: Diagnostic Issues in Thrombophilia

This conference addressed four basic questions regarding testing for genetic risk factors for thrombophilia:

• What tests should be done?
• When should testing be implemented?
• Who should be tested?
• How should testing be done?

Download the Diagnostic Issues in Thrombophilia conference report (2.1 K)

Read a series of related articles on thrombophilia published in the Archives of Pathology & Laboratory Medicine.

CAP Conference XXXI on Laboratory Monitoring of Anticoagulant Therapy

The following articles on anticoagulant therapy were presented at the conference and published in the Archives of Pathology & Laboratory Medicine.

• Conference Introduction (PDF, 111 K)
• Laboratory Monitoring of Oral Anticoagulant Therapy (PDF, 208 K)
• Laboratory Monitoring of Unfractionated Heparin Therapy (PDF, 302 K)
• The Clinical Use and Laboratory Monitoring of Low Molecular Weight Heparin, Danaparoid, Hirudin and Related Compounds, and Argatroban (PDF, 221 K)
• Future Directions (PDF, 500 K)

Coagulation Journal Articles

The following articles published in the Archives of Pathology & Laboratory Medicine offer pathologists further focus on coagulation and coagulation-related issues.

• D-dimer: Simple Test, Tough Problems
• External Quality Assurance of Fibrinogen Assays Using Normal Plasma
• The Use of Computerized Provider Order Entry to Improve the Effectiveness and Efficiency of Coagulation Testing
• International Normalized Ratio Versus Plasma Levels of Coagulation Factors in Patients on Vitamin K Antagonist Therapy
• External Quality Assurance of Antithrombin, Protein C, and Protein S Assays
• Improvement of Coagulation Laboratory Practice in Thailand
• The Laboratory Diagnosis of Platelet Disorders
• Laboratory Reporting of the International Normalized Ratio (PDF, 203 K)
• Effect of Fondaparinux on Coagulation Assays (PDF, 91 K)
• Laboratory Diagnosis of Dysfibrinogenemia

Coagulation Case Studies

The following cases studies focus on coagulation-related issues:

• Coagulation Specimen Handling Issues (2016 CGL-A Survey)
• Diagnosing heparin-induced thrombocytopenia (CAP TODAY, May 2000)
• How to work up hypercoagulability (CAP TODAY, January 2000)
• Addressing clinical etiologies of a prolonged aPTT (CAP TODAY, September 1999)
• When should low-molecular-weight heparin be monitored? (CAP TODAY, July 1999)
• Diagnosing antiphospholipid antibody syndrome (CAP TODAY, March 1999)
• Identifying vitamin K deficiency as the culprit in coagulation abnormality (CAP TODAY, January 1999)

CAP Surveys

The following CAP Surveys on coagulation and related topics along with their product codes are available for purchase:

• 11-Dehydrothomboxane B2 (TBX)
• Anticoagulant Monitoring (DBGN, FNPX, RVBN)
• Coagulation Limited (CGL, CGDF)
• Coagulation SVM (CGM)
• Coagulation Extended (CGE, CGEX)
• Coagulation Special Testing Series (CGS1, CGS2, CGS3, CGS4, CGS5, CGS6)
• Whole Blood Coagulation (WP3, WP4, WP6, WP9, WP10)
• Whole Blood D-dimer (WBDD)
• Platelet Function (PF, PF1, PIA, PLTM)
• Activated Clotting Time (CT, CT1, CT2, CT3, CT5)
• Thromboelastogram (TEG)

Join the Hemostasis and Thrombosis Committee

Learn more about our committee activities and how to join the Hemostasis and Thrombosis Committee.